The Design, Development, and Calibration of Cervical Abrasion Index of Treatment Needs Probe for Measurement of Cervical Abrasion.

Context: Although a common dental problem, there are no simple instruments or reliable methods to measure cervical abrasion. Aim: To study the design, development, calibration, efficacy, and compliance of usage of a novel Cervical Abrasion Index of Treatment Need (CAITN) probe to measure cervical abrasion. Settings and Design: The ex-vivo study was conducted as a part of comprehensive study for the development of standardized CAITN probe and index with a standard methodology for recording the abrasion. Materials and Methods: The compliance and usage of the probe were assessed by a standardized set of questionnaires to the interns followed by an ex-vivo study in 100 subjects. Gold standard comparisons with Vernier caliper, inter-examiner, and intra-examiner reliability were analyzed using SPSS. Results: Data from the questionnaire indicate that 100% of examiners had no difficulty in handling the instrument or measuring and reading the values. Comparison between the CAITN probe and the gold standard was statistically significant indicating a correlation for cervical abrasion measurement between the two methods (p < 0.001). The mean difference between the two measurements using the CAITN probe and gold standard method was calculated with paired t-test and was insignificant (p > 0.05). High statistical significant correlation was also found for intra-examiner and inter-examiner reliability measurement of CAITN probe (p < 0.001). Conclusion: The design and structure of the CAITN probe are standardized with a fair gold standard comparison and that the novel probe can be used as an effective tool to measure the depth of cervical abrasion and its treatment needs.

The Effect of Demineralization and Remineralization Cycles on the Bond Strength of Resin Composite to Enamel.

Toothwear is a growing concern, particularly in young adults. Prevention strategies remain of utmost importance and may involve the use of remineralising agents. If restorative treatment is indicated, adhesive techniques are recommended. It is unknown whether remineralising agents affect adhesion. METHOD: 77 bovine incisors were subjected to simulated toothwear by erosion (0.3% citric acid) and abrasion (oscillating toothbrush). Samples were randomly arranged into 5 test and 2 control groups (n=11). Each test group had a remineralising agent applied. Subsequently, composite was bonded to each sample and subjected to shear bond testing. Shear bond strength, mode of failure and enamel surface changes were analysed. RESULTS: There was no statistically significant difference for bond strength between groups (p=0.262). Mode of failure was statistically significant between groups (p⟨0.0001). Qualitative analysis showed a surface layer on samples remineralised by calcium silicate and stannous fluoride. Both groups had more adhesive failures. CONCLUSION: Within the limitations of this study, it can be concluded that the remineralising agents tested do not affect shear bond strength though surface layers created on the enamel influence the mode of failure. These 'sacrificial' surface layers have the potential to protect the underlying enamel structure.

Is toothwear associated with oral health related quality of life in adults in the UK?

OBJECTIVES: Toothwear may impact on an individual's everyday life, yet there is little research investigating the association between toothwear and oral health related quality of life (OHRQoL). The aim of the present study was to investigate the association between toothwear and OHRQoL in adults in the United Kingdom. BASIC RESEARCH DESIGN: This study involved secondary analysis of data from 5187 participants with toothwear in the Adult Dental Health Survey conducted in 2009. Toothwear was assessed using Smith and Knight criteria and the Basic Erosive Wear Index and classified as mild, moderate and severe. MAIN OUTCOME MEASURES: Correlation analyses were carried out between OHIP-14 total scores and toothwear type. Regression analyses investigated the association between toothwear and OHRQoL adjusting for demographic variables. RESULTS: There was a significant association between toothwear and OHRQoL, with more severe toothwear associated with greater oral health impact on daily life. The association between erosive toothwear and OHRQoL was significant for moderate and severe severities only. The adjusted linear regression model identified that toothwear accounted for 0.02% of the variance in total OHIP-14 scores. Females, younger individuals and less deprived individuals showed a greater association between toothwear and OHRQoL. CONCLUSIONS: In this general population sample, there was a small significant association between toothwear and OHRQoL impacts. However, the association was only significant for more severe categories of toothwear.

The association between erosive toothwear and gastro-oesophageal reflux-related symptoms and disease: A systematic review and meta-analysis.

OBJECTIVES: To conduct a systematic review and meta-analysis to explore the association between erosive toothwear and gastro-oesophageal reflux disease or symptoms (GERD/S). SOURCES: Electronic searches were performed in Scopus, Embase, and Web of Science databases for the identification of relevant studies, from 1980 until 2nd August 2019. STUDY SELECTION: The review protocol was registered on PROSPERO (CRD42018096959) and the review was conducted according to PRISMA guidelines. Observational studies which examined the association between erosive toothwear, and GERD/S were included and categorised according to the use of objective or subjective measures of GERD/S. Where possible, odds ratios (OR) and 95 % confidence intervals (CI) were derived and pooled in a meta-analysis. DATA: 27 studies were considered relevant for the qualitative synthesis and 19 studies were pooled. Significantly increased odds of erosive toothwear were observed in individuals with GERD/S. This trend was more strongly associated with objectively measured GERD/S (OR 4.13, 95 % CI 1.68-10.13), compared to subjectively measured GERD/S (OR 2.69, 95 % CI 1.13-6.38). Whilst heterogeneity was very high these trends remained in most sensitivity and subgroup analyses conducted. CONCLUSION: Individuals with GERD/S have a 2-4 fold increased odds ratio of also presenting with evidence of erosive toothwear compared with individuals who do not have GERD/S. CLINICAL SIGNIFICANCE: This review suggests the need for a multidisciplinary medical and dental approach to managing individuals who present with erosive toothwear or GERD/S. Timely referrals between oral health services and gastroenterology should be considered as part of effective diagnosis and management.

Influência do desequilíbrio oclusal na origem de lesão cervical não cariosa e recessão gengival: análise por elementos finitos / Influence of occlusal instability on the origin of non-carious cervical lesion and gingival recession: finite element analysis

Objetivo: avaliar o comportamento biomecânico de pré- -molar superior com presença de Lesões Cervicais Não Cariosas (LCNC) e submetido a três carregamentos oclusais distintos pelo método de elementos finitos tridimensional (3D). Material e método: nove modelos tridimensionais elásticos foram gerados, com propriedades ortotrópicas e isotrópicas: Hígido (H); LCNC não restaurada (LCNC) e LCNC restaurada com resina composta (RC); sendo todos estes modelos submetidos a três carregamentos: Axial (A), Oblíquo vestibular (V) e Oblíquo palatino (P). Os carregamentos tiveram intensidade de 150 N e a restrição de deslocamento foi realizada na base e lateral dos ossos cortical e medular. Os resultados foram gerados em tensão máxima e mínima principal. Resultados: O carregamento axial apresentou padrões de tensão mais favoráveis, independente da característica da região cervical. O carregamento palatino mostrou maior acúmulo de tensão de tração na região cervical vestibular e o carregamento vestibular resultou em maior tensão de compressão na tábua óssea vestibular. A presença de LCNC foi fator intensificador para o aumento da concentração de tensão na região cervical. A simulação da restauração com resina composta promoveu um comportamento biomecânico simular ao do hígido. Conclusões: que o carregamento palatino pode estar mais associado com a presença de LCNCs e o vestibular com a presença de recessão gengival. O ajuste oclusal e a restauração da LCNC são indicados para tornar o padrão de tensão mais favorável para o remanescente dentário.

Objective: to evaluate the biomechanical behavior of maxillary premolar with the presence of NCCL and submitted to three distinct occlusal loads, using the three-dimensional (3D) finite element analysis. Methods: nine three-dimensional elastic models were generated, with orthotropic and isotropic properties: Sound (H); Unrestored NCCL (NCCL) and NCCL restored with composite resin (RC); All models were submitted to three loads: Axial (A), Buccal (V) and Palataline (P). The loads intensity was 150 N and the displacement restriction was performed at the base and lateral of the cortical and medullary bones. The results were generated at maximum and minimum principal stress. Results: the axial loading presented more favorable stress pattern, independent of the characteristic of the cervical region. The palataline loading showed a greater concentration of tensile stress in the buccal cervical region and the buccal loading resulted in a higher compression stress in the buccal bone. The presence of NCCL was a relevant factor for increase concentration of stress in the cervical region. The simulation of the restoration with composite resin promoted a biomechanical behavior similar to that of the sound tooth. Conclusion that the palataline loading may be more associated with the presence of NCCLs and the vestibular with the presence of gingival recession. The occlusal adjustment and the restoration of NCCLs are indicated to produce the stress pattern more favorable for the dental remaining.

Protective effects of SnF2 - Part I. Mineral solubilisation studies on powdered apatite.

PURPOSE: To compare the ability of two active ingredients - sodium fluoride (NaF) and stannous fluoride (SnF2 ) - to inhibit hydroxyapatite (HAP) dissolution in buffered acidic media. METHODS: Two in vitro studies were conducted. HAP powder, which is representative of tooth mineral, was pretreated with: test solutions of NaF or SnF2 , 10 g solution per 300 mg HAP powder (Study 1); or NaF or SnF2 dentifrice slurry supernatants, 20 g supernate per 200 mg HAP powder for 1 minute followed by three washes with water, then dried (Study 2). About 50 mg of pretreated HAP was exposed to 25 ml of acid dissolution media adjusted to and maintained at pH 4.5 in a Metrohn Titrino reaction cell. Exposure of HAP to the media results in dissolution and release of hydroxide ion, increasing the pH of the solution. The increase in pH is compensated for by automatic additions of acid to maintain the original pH (4.5) of the reaction cell. Total volume of titrant added after 30 minutes was used to calculate the percentage reduction in dissolution versus non-treated HAP control. RESULTS: Both F sources provided protection against acid dissolution; however, in each study, SnF2 -treated HAP was significantly more acid-resistant than the NaF treated mineral. In study 1, at 280 ppm F, representing concentrations of F found in the mouth after in vivo dentifrice use, the reduction in HAP dissolution was 47.7% for NaF and 75.7% for the SnF2 -treated apatite (extrapolated). In study 2, the reduction in HAP dissolution was 61.3% for NaF and 92.8% for SnF2 -treated samples. Differences in percentage reduction were statistically significant (Paired-t test). CONCLUSIONS: Results of these studies demonstrate that both of the fluoride sources tested enhance the acid resistance of tooth mineral and that resistance is significantly greater after treatment with SnF2 compared with treatment of tooth mineral with NaF.

Protective effects of SnF2 - Part III. Mechanism of barrier layer attachment.

OBJECTIVE: To assess the ability of various fluoride salts to protect enamel against acid attack via a barrier mechanism. METHODS: Extracted human enamel specimens were cleaned and rinsed, then soaked in pooled human saliva for 1 hour to initiate formation of an early pellicle. Groups of three specimens each were etched for 10 minutes in 1% citric acid (pH 2.3), treated in a 1:3 slurry of dentifrice [1,100 ppm F as stannous fluoride (SnF2 ), 1,100 ppm F as sodium fluoride (NaF), 1,000 ppm F as sodium monofluorophosphate (SMFP), or 1,400 ppm F as amine fluoride (AmF)] and saliva for 2 minutes, exposed to 2% alizarin red-S (a calcium-selective dye) and rinsed again. The relative ability of each test product to deposit a barrier layer on the enamel surface was measured by its ability to protect against attachment of the calcium-selective dye. RESULTS: Specimens treated with the SnF2 dentifrice showed the least dye attachment, indicating a high level of surface protection. On a five-point scale, with 0 being no dye deposition (100% protection) and four being complete dye coverage (0% protection), the SnF2 -treated specimens scored an average of 0.25, with NaF scoring 3.4, SMFP scoring 3.4 and AmF scoring 3.7. Protection of the enamel surface was significantly higher for the SnF2 product than for the other products (P < 0.05), with no significant differences among the other three F salts. CONCLUSIONS: These results demonstrate that after an aggressive acid challenge, SnF2 deposits a barrier layer onto the pellicle-coated enamel surface, and the barrier layer which attaches onto acid challenged tooth surfaces is different from any that might be provided by treatment with the other fluoride compounds tested.

A randomised in situ trial, measuring the anti-erosive properties of a stannous-containing sodium fluoride dentifrice compared with a sodium fluoride/potassium nitrate dentifrice.

OBJECTIVES: To determine if a stabilised, stannous-containing sodium fluoride dentifrice provides greater enamel protection in situ against intraoral dietary erosive challenges compared with a sodium fluoride/potassium nitrate dentifrice. METHODS: A single-centre, investigator blind, randomised, supervised, two-treatment, non-brushing, four-period crossover in situ study was undertaken, with each test period being 15 days. Thirty-five healthy adult subjects were recruited to participate in the study, which included four erosive acid challenges per day. Subjects were randomised to product treatment, which included either: (1) a stannous-containing sodium fluoride dentifrice (Oral-B(®) Pro-Expert Sensitive) or (2) a sodium fluoride/potassium nitrate dentifrice (Sensodyne(®) Pronamel(®) ). Each study subject wore an intraoral appliance retaining two sterilised, polished human enamel samples for 6 hours/day. Subjects swished with an allocated dentifrice slurry twice a day and with 250 ml of orange juice for 10 minutes (25 ml/minute over a 10-minute period) four times per day. The primary and secondary outcomes for this study were enamel loss measured using contact profilometry at days 15 and 5, respectively, using parametric analysis methods. RESULTS: At day 15, a 38% lower enamel loss (P < 0.0001) was observed, with estimated medians of 2.03 µm (SE 0.247) and 3.30 µm (SE 0.379), in favour of the stannous-containing dentifrice. At day 5, specimens treated with the stannous-containing sodium fluoride dentifrice demonstrated 25% less enamel loss than those treated with the sodium fluoride/potassium nitrate dentifrice. Treatment differences at day 5 were also statistically significant (P < 0.05), with estimated medians of 1.37 µm (SE 0.177) and 1.83 µm (SE 0.223), respectively. CONCLUSIONS: Results of this in situ study suggest the stabilised, stannous-containing sodium fluoride dentifrice could be used to provide significantly greater protection to enamel from erosive acid challenge compared with that provided by conventional fluoride-containing products.

Prevalence of dentine hypersensitivity and study of associated factors: a European population-based cross-sectional study.

OBJECTIVES: Dentine hypersensitivity (DH) manifests as a transient but arresting oral pain. The incidence is thought to be rising, particularly in young adults, due to increases in consumption of healthy, yet erosive, diets. This study aimed to assess the prevalence of DH and relative importance of risk factors, in 18-35 year old Europeans. METHODS: In 2011, 3187 adults were enrolled from general dental practices in France, Spain, Italy, United Kingdom, Finland, Latvia and Estonia. DH was clinically evaluated by cold air tooth stimulation, patient pain rating (yes/no), accompanied by investigator pain rating (Schiff 0-3). Erosive toothwear (BEWE index 0-3) and gingival recession (mm) were recorded. Patients completed a questionnaire regarding the nature of their DH, erosive dietary intake and toothbrushing habits. RESULTS: 41.9% of patients reported pain on tooth stimulation and 56.8% scored ≥1 on Schiff scale for at least one tooth. Clinical elicited sensitivity was closely related to Schiff score and to a lesser degree, questionnaire reported sensitivity (26.8%), possibly reflecting the transient nature of the pain, alongside good coping mechanisms. Significant associations were found between clinically elicited DH and erosive toothwear and gingival recession. The questionnaire showed marked associations between DH and risk factors including heartburn/acid reflux, vomiting, sleeping medications, energy drinks, smoking and acid dietary intake. CONCLUSION: Overall, the prevalence of DH was high compared to many published findings, with a strong, progressive relationship between DH and erosive toothwear, which is important to recognise for patient preventive therapies and clinical management of DH pain.